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T15641K777
K777 is a potent, orally active and irreversible inhibitor of cysteine protease. K777 is a potent CYP3A4 inhibitor (IC50= 60 nM). K777 is also a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 irreversibly inhibits Cruzain, which is the major cysteine protease of Trypansoma cruzi, and cathepsins B and L. K777 targets cathepsin-mediated cell entry and wxibits a broad-spectrum antiviral activity. K777 inhibits EBOV and SARS-CoV pseudovirus entry with IC50 values of 0.87
价 格:¥电议型 号:T15641产 地:中国大陆
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T8331NUN82647NUN82647,Inhibitor,NUN 82647,inhibit,Apoptosis,QBS,NUN-82647
NUN82647 is an Inhibitor of cell cycle at G2 phase, and apoptosis inducer.
价 格:¥电议型 号:T8331产 地:中国大陆
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T27371FR-167356
FR-167356 is a specific inhibitor of a3 isoform vacuolar type H?-ATPase with IC50s of 170 nM, 370 nM and 220 nM for osteoclast plasma membranes, renal brush border membranes and macrophage microsomes. FR-167356 reduces bone metastasis of B16-F10 cells.
价 格:¥电议型 号:T27371产 地:中国大陆
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TP1881L1Pep 2-8 ammonium salt(1541011-97-5 free base)Pep 2 8 ammonium salt(1541011 97 5 free base),Pep 28 am
Pep 2-8 ammonium salt is Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.
价 格:¥电议型 号:TP1881L1产 地:中国大陆
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TN4871PyrolinPyrolin
Pyrolin has a strong antifungal activity and exerts a potent impact on the ultrastructure of M.fructicola.
价 格:¥电议型 号:TN4871产 地:中国大陆
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T7400RRX-001Parasite,RRx-001,RRX 001,Apoptosis,Inhibitor,inhibit,RRX001
RRx-001 is a potent inhibitor ofglucose 6-phosphate dehydrogenase(G6PD) and with potent antimalarial activity
价 格:¥电议型 号:T7400产 地:中国大陆
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TQ0015PRN1371inhibit,CSF1R,PRN 1371,Inhibitor,colony stimulating factor 1 receptor,c-Fms,CSF-1R,FGFR,CSF-1
PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).
价 格:¥电议型 号:TQ0015产 地:中国大陆
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TP1882L1Orphanin FQ(1-11) acetate(178249-41-7 free base)Orphanin FQ(1 11) acetate(178249 41 7 free base),Orp
Peptide fragment containing amino acids 1-11 of Nociceptin. Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM); displays no affinity for opioid receptors, including μ, δ, κ1 and κ3 receptors (Ki >1000 nM). Displays analgesic properties in CD-1 mice.
价 格:¥电议型 号:TP1882L1产 地:中国大陆
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T60032BRM/BRG1 ATP Inhibitor-2Epigenetic Reader Domain,Inhibitor,BRM/BRG1 ATP Inhibitor 2,inhibit,BRM/BRG1
BRM/BRG1 ATP Inhibitor-2 is an inhibitor of BRG1/BRM ATPase and can be used in studies about the treatment of BAF-related disorders.
价 格:¥电议型 号:T60032产 地:中国大陆
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T7741DS-1001binhibit,DS 1001b,Inhibitor,Isocitrate Dehydrogenase (IDH),DS-1001b,DS1001b
DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)
价 格:¥电议型 号:T7741产 地:中国大陆
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T9041AES-350Histone deacetylases,AES 350,MV4-11,AES-350,Apoptosis,acute myeloid leukemia,AML,Inhibitor,in
AES-350 is a potent and orally active HDAC6 inhibitor(IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively). It is also against HDAC-3, -8, and -11 in an enzymatic activity assay with IC50 values of 0.187 μM, 0.245 μM, and >1μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research.
价 格:¥电议型 号:T9041产 地:中国大陆
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T7815LAOD9604 acetate(221231-10-3 free base)AOD9604 acetate(221231103 free base),AOD-9604 acetate(221231-1
AOD9604 acetate is a potential anti-obesity peptide based on the human growth hormone.
价 格:¥电议型 号:T7815L产 地:中国大陆
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TP1545L1FFAGLDD amine saltFFAGLDD amine salt
FFAGLDD amine salt is MMP9 selective cleavage peptides, which used for cytosolic delivery of Doxorubi-cin (DOX) and achieve temporally and spatially controlled slow drug delivery and release.
价 格:¥电议型 号:TP1545L1产 地:中国大陆
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T7356PTP1B-IN-1Inhibitor,PTP-1B-IN-1,PTP1BIN1,inhibit,Phosphatase,PTP1B IN 1
PTP1B-IN-1 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)
价 格:¥电议型 号:T7356产 地:中国大陆
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T74512-Cyanopyrimidineinhibit,Cathepsin,protease,2-Cyanopyrimidine,cysteine,2Cyanopyrimidine,osteoporos,2
2-cyano-Pyrimidine is inhibitor of cathepsin K(IC50 : 170 nM)
价 格:¥电议型 号:T7451产 地:中国大陆
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T24905TT01001
TT01001 is a selective agonist of mitoNEET and reduces oxidative stress injury and neuronal apoptosis by improving mitochondrial dysfunction. TT01001 can be used in studies about the treatment of type II diabetes.
价 格:¥电议型 号:T24905产 地:中国大陆
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T61016EMI1
EMI1 is an inhibitor of EGFR ex19del/T790M/C797S and EGFR L858R/T790M/C797S. EMI1 has research value in the research of mutant EGFR-associated, drug-resistant non-small-cell lung cancer (NSCLC).
价 格:¥电议型 号:T61016产 地:中国大陆
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TN6901Methyl myristateB16F10,Methyl myristate,melanin,myristic acid,inhibit,Inhibitor
Methyl myristate is a natural product.
价 格:¥电议型 号:TN6901产 地:中国大陆
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T38344Lalistat 1
Lalistat 1 is an inhibitor of lysosomal acid lipase (LAL, IC50 = 68 nM) and IgA1 protease for H. influenzae. Lalistat 1 can be used in studies about niemann-pick type C diseases.
价 格:¥电议型 号:T38344产 地:中国大陆